Lipitor is a brand name for the drug atorvastatin, which is used to treat high cholesterol levels. According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and antihistamines. However, it is important to note that there may be individual differences in how medications interact with each other, so it is always best to consult with a healthcare provider before taking any new medications.

One antihistamine that may interact with Lipitor is fexofenadine, which is sold under the brand name Allegra. According to Verywell Health [3], taking fexofenadine with Lipitor may increase the risk of muscle-related side effects, such as muscle pain or weakness. It is recommended to avoid taking these medications together or to closely monitor for any potential side effects if they are used together.

Another medication that may interact with Lipitor is ritonavir-boosted nirmatrelvir, which is sold under the brand name Paxlovid. According to the COVID-19 Treatment Guidelines [2], taking Paxlovid with Lipitor may increase the levels of Lipitor in the blood, which can increase the risk of muscle-related side effects. It is recommended to avoid taking these medications together or to closely monitor for any potential side effects if they are used together.

In conclusion, while there are no known drug interactions between Lipitor and antihistamines, it is important to consult with a healthcare provider before taking any new medications. It is also important to be aware of potential interactions with other medications, such as fexofenadine and Paxlovid, which may increase the risk of muscle-related side effects when taken with Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/ritonavir-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/
[3] https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202