Methotrexate is a medication that is commonly used to treat various conditions such as cancer, rheumatoid arthritis, and psoriasis. However, it is important to consider the age limitations for its use.

According to the sources provided, there is no specific maximum age for the use of methotrexate. The drug patent information [1] and the FDA label [3] do not mention any age restrictions for its use. This suggests that methotrexate can be prescribed to individuals of all ages, including older adults.

However, it is worth noting that the National Center for Biotechnology Information (NCBI) book on methotrexate [2] does mention that caution should be exercised when prescribing methotrexate to older adults. This is because older adults may be more susceptible to certain side effects and may require dose adjustments or closer monitoring. The book recommends considering the individual's overall health, organ function, and potential drug interactions when prescribing methotrexate to older adults.

In conclusion, while there is no specific maximum age for methotrexate use, caution should be exercised when prescribing it to older adults. It is important for healthcare professionals to carefully evaluate the individual's overall health and consider potential risks and benefits before prescribing methotrexate. Regular monitoring and dose adjustments may be necessary to ensure the safe and effective use of the medication.

Sources:
[1] Drug Patent Watch. Methotrexate. Retrieved from: https://www.drugpatentwatch.com/p/tradename/METHOTREXATE
[2] National Center for Biotechnology Information. Methotrexate. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK556114/
[3] U.S. Food and Drug Administration. Methotrexate. Retrieved from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008085s066lbl.pdf