After reviewing the provided sources, there is no evidence to suggest that Lipitor (atorvastatin) increases opioid potency. Lipitor is a medication used to lower cholesterol levels, while opioids are a class of drugs used for pain management. The sources do not indicate any interaction between Lipitor and opioids that would lead to an increase in opioid potency.
The first source [1] provides information about Lipitor's patent status, but it does not mention any interaction with opioids. The second source [2] is a study that examines the effects of atorvastatin on inflammation and pain in rats. While the study found that atorvastatin reduced inflammation and pain, it did not investigate any interaction with opioids. The third source [3] is a clinical trial that evaluated the efficacy and safety of a combination of atorvastatin and ezetimibe in patients with high cholesterol. The study did not investigate any interaction with opioids.
In conclusion, based on the provided sources, there is no evidence to suggest that Lipitor increases opioid potency. However, it is always important to consult with a healthcare provider before taking any new medications, especially if you are already taking opioids.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/
[3] https://www.nejm.org/doi/10.1056/NEJMoa061894