Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce fever. Lipitor, on the other hand, is a statin medication used to lower cholesterol levels in the blood.

According to Drugs.com, there is a moderate interaction between ibuprofen and Lipitor, which means that they may interact with each other and cause unwanted side effects. Taking ibuprofen with Lipitor may increase the risk of developing muscle-related side effects, such as muscle pain, weakness, and rhabdomyolysis, a rare but serious condition that can cause kidney damage.

The NHS advises that if you need to take painkillers while taking Lipitor, it is generally safe to take paracetamol instead of ibuprofen. Paracetamol is a painkiller that does not interact with Lipitor and is less likely to cause side effects. However, if you need to take ibuprofen, it is recommended to take it at least two hours before or after taking Lipitor to reduce the risk of interaction.

In conclusion, while it is generally safe to take ibuprofen and Lipitor together, there is a risk of interaction between the two drugs. It is advisable to avoid taking ibuprofen with Lipitor and instead use an alternative painkiller such as paracetamol. If ibuprofen is necessary, it is best to take it at least two hours before or after taking Lipitor to minimize the risk of interaction. As with any medication, it is important to consult a healthcare professional before taking any new medication or combination of medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/IBUPROFEN
[2] https://www.drugs.com/drug-interactions/ibuprofen-with-lipitor-1310-0-276-128.html
[3] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/