Grapefruit contains compounds that can interfere with the metabolism of certain medications, including some statins like Lipitor [1][2]. These compounds can inhibit an enzyme in the liver that is responsible for breaking down drugs, leading to higher levels of the drug in the bloodstream than intended. This can increase the risk of side effects or toxicity.
Other medications that can interact with grapefruit include some blood pressure drugs, immunosuppressants, and anti-anxiety medications, among others [3]. It is important to check with a healthcare provider or pharmacist before consuming grapefruit or grapefruit juice while taking any medication, as the interaction can vary depending on the specific drug and dose.
In conclusion, grapefruit can interact with certain medications, including Lipitor, due to compounds that inhibit drug metabolism. Other medications that can interact with grapefruit include some blood pressure drugs, immunosuppressants, and anti-anxiety medications, among others. It is important to check with a healthcare provider or pharmacist before consuming grapefruit or grapefruit juice while taking any medication.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin
[3] https://www.nhs.uk/common-health-questions/medicines/does-grapefruit-affect-my-medicine/