Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the body [1]. However, one of the side effects of Lipitor is hyperglycemia, or high blood sugar levels [2]. While the exact mechanism behind this side effect is not fully understood, it is believed that statins like Lipitor may interfere with insulin sensitivity and glucose metabolism [3].

To manage Lipitor-induced hyperglycemia, there are several medications that can be used. One option is to switch to a different statin medication that is less likely to cause hyperglycemia, such as pravastatin or rosuvastatin [2]. Another option is to add a medication that can help regulate blood sugar levels, such as metformin or a dipeptidyl peptidase-4 (DPP-4) inhibitor [3]. These medications work by improving insulin sensitivity and reducing glucose production in the liver.

It is important to note that any medication changes should be made under the guidance of a healthcare professional. They can evaluate the individual's specific situation and make recommendations based on their medical history, current medications, and other factors.

Sources:
[1] DrugPatentWatch. Lipitor. https://www.drugpatentwatch.com/p/tradename/LIPITOR. Accessed 26 Oct 2021.
[2] National Center for Biotechnology Information. Lipitor-induced hyperglycemia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369709/. Accessed 26 Oct 2021.
[3] Mayo Clinic. Statin side effects: Weigh the benefits and risks. https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013. Accessed 26 Oct 2021.