Advil is a brand name for the drug ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. According to the Advil website [2], it is recommended to take Advil with food or milk to help prevent stomach irritation. This is because ibuprofen can irritate the stomach lining, leading to gastrointestinal problems such as ulcers and bleeding. Taking Advil with food or milk can help to reduce the risk of stomach irritation and protect the stomach lining.

The Drugs.com website [3] also recommends taking ibuprofen with food or milk to help prevent stomach irritation. However, it is important to note that taking ibuprofen with food may slow down the absorption of the drug, which could delay the onset of pain relief. If you need fast pain relief, it may be better to take ibuprofen on an empty stomach, but only if you do not have a history of stomach problems or ulcers.

In conclusion, it is generally recommended to take Advil with food or milk to help prevent stomach irritation [2][3]. However, if you need fast pain relief, taking ibuprofen on an empty stomach may be an option, but only if you do not have a history of stomach problems or ulcers [3]. It is important to follow the recommended dosage and consult with a healthcare professional if you have any concerns or questions about taking Advil or ibuprofen [2][3].

Sources:
[2] https://www.advil.com/faqs-en/advil-pain/
[3] https://www.drugs.com/medical-answers/you-ibuprofen-empty-stomach-3572019/