Advil is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce fever. While Advil is generally considered safe and effective, it may cause some side effects, including stomach discomfort. According to the guidelines provided by the Hospital for Special Surgery [2], taking Advil with food or milk can help reduce the risk of stomach discomfort. It is also recommended to avoid alcohol and smoking, which can increase the risk of stomach irritation.

The drug label for Advil [3] warns that it may cause stomach bleeding, which can be life-threatening. This risk is higher in people who are over 60 years old, have a history of stomach ulcers or bleeding, take blood thinners or corticosteroids, or take Advil for a long period of time.

It is important to follow the recommended dosage and duration of treatment when taking Advil. Taking more than the recommended dose or taking it for a longer period of time than recommended can increase the risk of side effects, including stomach discomfort.

In summary, while Advil is generally safe and effective, it may cause stomach discomfort and other side effects. Following the recommended guidelines for use, such as taking it with food or milk and avoiding alcohol and smoking, can help reduce the risk of stomach discomfort. However, it is important to be aware of the potential risks associated with Advil, including stomach bleeding, and to follow the recommended dosage and duration of treatment.

Sources:
[2] Hospital for Special Surgery. Guidelines to Reduce the Side Effects of NSAIDs. Retrieved from https://www.hss.edu/conditions_guidelines-reduce-side-effects-nsaids.asp
[3] MedlinePlus. Ibuprofen. Retrieved from https://medlineplus.gov/druginfo/meds/a682159.html