Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the body. According to the Drug Patent Watch [1], there are no known interactions between atorvastatin and plant-based substitutes. However, it is always recommended to consult with a healthcare professional before combining any medications or supplements.

There are various plant-based substitutes that can help lower cholesterol levels in the body. According to the British Heart Foundation [2], some of these include:

1. Soluble fiber: Found in foods such as oats, barley, and fruits, soluble fiber can help reduce cholesterol levels.

2. Sterols and stanols: These substances are found in plant-based foods and can help block the absorption of cholesterol in the body.

3. Soy protein: Found in foods such as tofu and soy milk, soy protein can help reduce cholesterol levels.

4. Nuts: Eating a handful of nuts per day, such as almonds or walnuts, can help reduce cholesterol levels.

It is important to note that while these plant-based substitutes can help lower cholesterol levels, they should not be used as a substitute for medication prescribed by a healthcare professional.

Zetia is another medication used to lower cholesterol levels. According to Medical News Today [3], there are no known interactions between Zetia and plant-based substitutes. However, as with Lipitor, it is always recommended to consult with a healthcare professional before combining any medications or supplements.

Sources:
1. https://www.drugpatentwatch.com/p/tradename/LIPITOR
2. https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/cholesterol-lowering-alternatives
3. https://www.medicalnewstoday.com/articles/zetia