Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor works by inhibiting the enzyme HMG-CoA reductase, which is responsible for producing cholesterol in the liver. While Lipitor is effective in reducing cholesterol levels, it may also impact the absorption of certain supplements.

A study published in the Journal of Clinical Pharmacology [2] found that atorvastatin, the active ingredient in Lipitor, may decrease the absorption of vitamin D. The study observed a significant decrease in vitamin D levels in patients taking atorvastatin compared to those not taking the medication. Vitamin D is essential for maintaining bone health and supporting the immune system, so a decrease in its absorption may have negative health consequences.

According to the National Institutes of Health Office of Dietary Supplements [3], taking Lipitor may also impact the absorption of other fat-soluble vitamins, such as vitamin A, vitamin E, and vitamin K. These vitamins require dietary fat for absorption, and since Lipitor works by reducing the amount of cholesterol in the body, it may also reduce the absorption of these vitamins.

In conclusion, Lipitor may impact the absorption of certain supplements, including vitamin D and other fat-soluble vitamins. Patients taking Lipitor should speak with their healthcare provider about the potential impact on their supplement regimen and discuss any necessary adjustments.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://pubmed.ncbi.nlm.nih.gov/18754003/
[3] https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/