Based on the available information, there is no direct evidence or indication that Lipitor, a medication used to treat high cholesterol, worsens the side effects of salt substitutes.

Salt substitutes are often used by individuals with high blood pressure or those who are restricting their sodium intake. These substitutes typically contain potassium chloride as a replacement for sodium. Potential side effects of salt substitutes can include gastrointestinal symptoms such as nausea, vomiting, or diarrhea, especially when consumed in excess [1].

Lipitor (atorvastatin) is a statin medication used to lower cholesterol levels in the blood. Common side effects of Lipitor include muscle pain, liver damage, and increased blood sugar levels [2].

There are no known interactions between Lipitor and potassium-based salt substitutes that would suggest an exacerbation of side effects [3]. However, it is always important to consult with a healthcare provider or pharmacist for personalized advice regarding medication use and potential interactions.

Sources:
[1] "Salt Substitutes." Mayo Clinic, Mayo Foundation for Medical Education and Research, 11 Feb. 2022, www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/salt/art-20045454.
[2] "Lipitor." MedlinePlus, U.S. National Library of Medicine, 11 Feb. 2022, medlineplus.gov/druginfo/meds/a697043.html.
[3] "Atorvastatin (Oral Route) Interactions." Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Jan. 2022, www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/interactions/drg-20067010.