Lipitor, also known as atorvastatin, is a commonly prescribed medication used to lower cholesterol levels in the body. According to Drug Patent Watch [1], Lipitor has been found to interact with several medications. For instance, the medication can interact with cyclosporine, which is used to prevent organ rejection after a transplant. The interaction can lead to increased levels of Lipitor in the body, which can cause serious side effects such as muscle damage.
Additionally, the medication can interact with fibrates, which are used to lower triglyceride levels in the body. The interaction can also cause muscle damage, and it is recommended that the combination of Lipitor and fibrates be avoided. Lipitor can also interact with other medications such as erythromycin, clarithromycin, and certain antifungal medications. These interactions can increase the levels of Lipitor in the body, leading to an increased risk of side effects.
According to a study published in the US National Library of Medicine [2], Lipitor can also interact with some herbal supplements such as St. John's Wort. The study found that St. John's Wort can decrease the effectiveness of Lipitor, leading to increased cholesterol levels in the body.
The American Heart Association [3] also warns that Lipitor can interact with grapefruit juice, which can increase the levels of the medication in the body. This can lead to an increased risk of side effects such as muscle damage.
In conclusion, Lipitor can interact with several medications, including cyclosporine, fibrates, erythromycin, clarithromycin, certain antifungal medications, and St. John's Wort. The medication can also interact with grapefruit juice. It is essential to inform your doctor of all the medications and supplements you are taking before starting Lipitor to avoid potential interactions and serious side effects.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/
[3] https://www.heart.org/en/health-topics/consumer-healthcare/medication-information/medication-interactions-food-supplements-and-other-drugs