Lipitor is a medication used to lower cholesterol levels in the blood. It contains the active ingredient atorvastatin, which works by inhibiting an enzyme that produces cholesterol in the liver. According to the sources provided, there is no specific recommended dosage for Lipitor in patients with liver issues.
The first source, Drug Patent Watch [1], provides information on the patent status and expiration of Lipitor. However, it does not provide any information on the recommended dosage for patients with liver issues.
The second source, a book published by the National Center for Biotechnology Information [2], provides an overview of atorvastatin and its effects on the liver. It notes that atorvastatin can cause liver damage in rare cases, but this is usually reversible upon discontinuation of the medication. The book does not provide any specific dosage recommendations for patients with liver issues.
The third source, the FDA label for Lipitor [3], provides detailed information on the medication, including dosing recommendations. However, it does not provide any specific guidance on dosing for patients with liver issues. It does caution that Lipitor should be used with caution in patients with a history of liver disease, and liver function tests should be monitored regularly.
In conclusion, based on the sources provided, there is no specific recommended dosage for Lipitor in patients with liver issues. Patients with liver disease should use caution when taking Lipitor, and liver function tests should be monitored regularly. It is important for patients to discuss their individual circumstances with their healthcare provider to determine the appropriate dosage and course of treatment.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/books/NBK548236/
[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf