Lipitor (atorvastatin) is a medication commonly prescribed to lower cholesterol levels. When considering potential interactions with nonsteroidal anti-inflammatory drugs (NSAIDs), caution is advised. NSAIDs like ibuprofen and naproxen are known to increase the risk of kidney damage when taken with certain medications, including statins like Lipitor. The combination of NSAIDs and Lipitor may lead to a higher risk of kidney problems due to the potential additive effect on kidney function. Patients taking Lipitor should consult their healthcare provider before taking NSAIDs to minimize the risk of adverse effects. It is essential to discuss any concerns or potential interactions with a healthcare professional to ensure safe and effective treatment. [2][3]

Sources:
[2] https://www.healthline.com/health/drugs/lipitor-interactions
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913168/