Lipitor is a brand name for atorvastatin, which is a medication used to lower cholesterol levels in the blood. While Lipitor is generally considered safe and effective, it can cause muscle weakness and even rhabdomyolysis in some cases.

Rhabdomyolysis is a rare but serious condition that can occur when muscle tissue breaks down and releases a protein called myoglobin into the bloodstream. This can cause kidney damage or failure, and in severe cases, can be life-threatening [3].

According to a study published in the Journal of Clinical Lipidology, muscle symptoms associated with atorvastatin use typically occur within the first few weeks of treatment and resolve within 4-6 weeks after discontinuing the medication [2]. However, in rare cases, muscle symptoms can persist for several months or even years after stopping the medication [2].

It is important to note that muscle symptoms associated with atorvastatin use are generally mild and reversible, and serious complications such as rhabdomyolysis are rare. However, if you experience muscle weakness or pain while taking Lipitor, you should contact your doctor right away [1].

In summary, muscle weakness associated with Lipitor use typically occurs within the first few weeks of treatment and resolves within 4-6 weeks after discontinuing the medication. However, in rare cases, muscle symptoms can persist for several months or even years after stopping the medication. If you experience muscle weakness or pain while taking Lipitor, you should contact your doctor right away.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949584/
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/expert-answers/rhabdomyolysis/faq-20057817