Lipitor is a medication used to lower cholesterol levels in the blood. It works by inhibiting an enzyme called HMG-CoA reductase, which is involved in the production of cholesterol in the liver. The drug is effective in reducing the absorption of dietary fats, but the exact amount of fat reduction is not specified in the provided sources.

According to the Drug Patent Watch [1], the active ingredient in Lipitor, atorvastatin calcium, is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. The drug is administered orally and is rapidly absorbed from the gastrointestinal tract. It undergoes extensive first-pass metabolism in the liver, and its primary metabolites are pharmacologically active.

The Office of Dietary Supplements [2] notes that the absorption of fat-soluble vitamins, including vitamin D, can be affected by the use of medications that reduce fat absorption. However, the fact sheet does not provide any specific information about the effect of Lipitor on vitamin D absorption.

A study published in the Journal of Clinical Investigation [3] investigated the effect of atorvastatin on the absorption of dietary cholesterol and triglycerides in healthy volunteers. The study found that atorvastatin reduced the absorption of both cholesterol and triglycerides, but the magnitude of the reduction varied among individuals.

In conclusion, while Lipitor is known to reduce the absorption of dietary fats, the exact amount of fat reduction is not specified in the provided sources. It is important to note that the absorption of fat-soluble vitamins may also be affected by the use of the medication. Patients should consult with their healthcare provider for more information about the potential effects of Lipitor on their individual health.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312230/