Lipitor (atorvastatin) is a medication used to lower cholesterol levels, while NSAIDs (nonsteroidal anti-inflammatory drugs) are a group of medications used to relieve pain and inflammation. Combining Lipitor and NSAIDs can potentially increase the risk of certain side effects.
According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and NSAIDs. However, this does not mean that there are no risks associated with combining these medications.
A study published in the International Journal of Cancer [2] found that the use of NSAIDs was associated with a reduced risk of breast cancer in women taking Lipitor. However, the study also noted that the combination of Lipitor and NSAIDs may increase the risk of liver damage.
Another study published in PubMed [3] found that the use of NSAIDs with statins (a class of medications that includes Lipitor) was associated with an increased risk of kidney damage. The study also noted that the risk was greater in older patients and those with pre-existing kidney disease.
In conclusion, while there are no known drug interactions between Lipitor and NSAIDs, there are potential risks associated with combining these medications. Patients should speak with their healthcare provider before taking these medications together, especially if they have pre-existing liver or kidney disease.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.23718
[3] https://pubmed.ncbi.nlm.nih.gov/18548583/