Lipitor is a medication that is used to lower cholesterol levels in the body. The dosage of Lipitor was changed due to safety concerns. In 2012, the FDA issued a safety communication regarding the use of statin drugs, including Lipitor, stating that high doses of these drugs could increase the risk of muscle damage, liver damage, and diabetes [2]. As a result, the recommended dosage of Lipitor was lowered to reduce the risk of these side effects [3].
Lipitor is a brand name for the drug atorvastatin, which is a type of statin medication. The patent for Lipitor expired in 2011, which led to the introduction of generic versions of the drug [1]. The dosage of Lipitor may vary depending on the individual's medical condition and response to treatment. The recommended starting dose of Lipitor is typically 10 or 20 mg per day, and the maximum recommended dose is 80 mg per day [3].
In conclusion, the dosage of Lipitor was changed due to safety concerns regarding the use of high doses of statin drugs. The FDA issued a safety communication in 2012, which led to the lowering of the recommended dosage of Lipitor to reduce the risk of muscle damage, liver damage, and diabetes. The recommended starting dose of Lipitor is typically 10 or 20 mg per day, and the maximum recommended dose is 80 mg per day.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-important-safety-label-changes-cholesterol-lowering-statin-drugs
[3] https://www.healthline.com/health/drugs/lipitor-dosage