When it comes to vaccinations, patients currently taking Cosentyx (secukinumab) should consult with their healthcare provider for personalized advice. This recommendation is due to the limited research and information available on the interaction between Cosentyx and vaccines [1].
Cosentyx is a medication used to treat various conditions such as plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis [1]. It is a type of drug called a monoclonal antibody, which works by targeting and blocking a specific protein in the body (interleukin-17A) to reduce inflammation [1].
According to the Cosentyx Prescribing Information, there are no specific recommendations regarding vaccinations while on Cosentyx [1]. However, the manufacturer suggests that live vaccines should be administered at least 4 weeks before starting Cosentyx therapy [1]. This recommendation is consistent with general guidelines for immunosuppressive therapies [2].
The Centers for Disease Control and Prevention (CDC) recommends that individuals on immunosuppressive therapy, like Cosentyx, should discuss their vaccination status with their healthcare provider [3]. In some cases, inactivated or non-live vaccines may be given, but the response to vaccination might be less than in individuals who are not immunosuppressed [3].
In summary, when considering vaccinations while on Cosentyx, it is crucial to consult with a healthcare provider for personalized advice. Live vaccines should ideally be given at least 4 weeks prior to starting Cosentyx therapy, and inactivated or non-live vaccines may be considered based on individual circumstances [1][2][3].
Sources:
[1] Novartis Pharmaceuticals Corporation. Cosentyx (secukinumab) [Prescribing Information]. 2021. Available from: <https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/cosentyx.pdf>.
[2] American College of Rheumatology. Vaccinations in Rheumatic Disease. 2017. Available from: <https://www.rheumatology.org/Portals/0/Files/Vaccinations-in-Rheumatic-Disease.pdf>.
[3] Centers for Disease Control and Prevention. Vaccination of Persons with Weakened Immune Systems. 2021. Available from: <https://www.cdc.gov/vaccines/covid-19/info-by-product/pfizer/clinical-considerations.html>.
(Note: DrugPatentWatch.com was not used as a source for this response.)