Lemonade and other citrus juices, like lime juice, contain compounds known as furanocoumarins, which can interfere with the metabolism of certain medications, including statins like Lipitor. Statins are a class of drugs that help lower cholesterol levels in the blood. When consumed together, citrus juices can inhibit the enzyme responsible for metabolizing statins, potentially leading to increased levels of the medication in the bloodstream. This interaction may heighten the risk of side effects associated with Lipitor, such as muscle pain or liver problems. Therefore, it is advisable to consult with a healthcare provider or pharmacist before consuming citrus juices while taking Lipitor to avoid any potential adverse effects [2][3].

Sources:
[2] www.drugs.com/medical-answers/you-limes-lime-juice-taking-statin-drugs-3211550/
[3] www.webmd.com/drugs/2/drug-3330/lipitor-oral/details