Lipitor, also known as Atorvastatin, is a prescription medication used to lower cholesterol levels and reduce the risk of heart attack and stroke [3]. It is important to note that Lipitor can interact with other drugs, which can affect its effectiveness or cause unwanted side effects.

According to GoodRx [2], there are 409 drugs that can potentially interact with Lipitor, including common medications such as aspirin, ibuprofen, and vitamins. These interactions can range from mild to severe and can affect how Lipitor works in the body. For example, Lipitor can increase the risk of muscle damage when taken with certain medications such as fibrates, which are used to lower cholesterol levels [2].

Drug Patent Watch [1] lists some common drug interactions with Lipitor, including antifungal medications such as itraconazole and ketoconazole, which can increase the risk of muscle damage. Additionally, certain antibiotics such as erythromycin and clarithromycin can increase the levels of Lipitor in the body, which can lead to side effects such as muscle pain and weakness [1].

WebMD [3] also notes that grapefruit juice can interact with Lipitor and increase the risk of side effects. This is because grapefruit juice can increase the levels of Lipitor in the body, which can lead to an increased risk of muscle damage. It is recommended to avoid grapefruit juice while taking Lipitor [3].

In conclusion, Lipitor can interact with a wide range of medications and substances, including common over-the-counter medications and grapefruit juice. It is important to inform your healthcare provider of all medications and supplements you are taking to avoid potential interactions and ensure the safe and effective use of Lipitor [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/atorvastatin/interactions
[3] https://www.webmd.com/drugs/2/drug-3330/lipitor-oral/details