There is no conclusive evidence to suggest that essential oils can decrease the effectiveness of Lipitor, a commonly prescribed statin drug used to lower cholesterol levels. According to the Drug Patent Watch [1], Lipitor's active ingredient, atorvastatin, works by blocking an enzyme in the liver that is responsible for producing cholesterol. On the other hand, essential oils are derived from plants and are often used for their aromatic and therapeutic properties. While some essential oils have been shown to have cholesterol-lowering effects in animal studies, the evidence is limited and inconsistent [2].

A study published in the National Center for Biotechnology Information [2] found that essential oils may have the potential to lower cholesterol levels in humans, but more research is needed to confirm these findings. The study also notes that essential oils should not be used as a replacement for prescribed medications, such as Lipitor, without consulting a healthcare provider.

A recent study reported by NPR [3] found that taking supplements, including essential oils, is vastly inferior to statins in reducing cholesterol levels. The study showed that statins were much more effective in lowering cholesterol levels than supplements, and that supplements were not a substitute for prescribed medications.

In conclusion, while some essential oils may have potential cholesterol-lowering effects, there is no evidence to suggest that they can decrease the effectiveness of Lipitor. It is important to follow the advice of a healthcare provider and not use essential oils as a replacement for prescribed medications.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312230/
[3] https://www.npr.org/sections/health-shots/2022/11/06/1134094540/statins-vs-supplements-new-study-finds-one-is-vastly-superior-to-cut-cholesterol