There is some evidence to suggest that dietary fat can impact the side effects of Lipitor (atorvastatin), a medication used to treat high cholesterol. According to DrugPatentWatch.com, Lipitor is one of the most commonly prescribed medications in the United States, and its side effects can include muscle pain, liver damage, and digestive issues [1].
Studies have shown that a diet high in saturated and trans fats can increase the risk of muscle pain and liver damage as a result of taking Lipitor [2][3]. Additionally, a study published in the Journal of Clinical Lipidology found that a diet high in monounsaturated fats, such as those found in olive oil, can actually reduce the risk of muscle pain and liver damage in patients taking Lipitor [4].
It is important to note that while diet can impact the side effects of Lipitor, it does not affect the drug's ability to lower cholesterol levels [5]. Patients should consult with their healthcare provider before making any changes to their diet or medication regimen.
In summary, a diet high in saturated and trans fats can increase the risk of muscle pain and liver damage as a result of taking Lipitor, while a diet high in monounsaturated fats can reduce this risk. Patients should consult with their healthcare provider before making any changes to their diet or medication regimen.
Sources:
1. "[Lipitor (Atorvastatin Calcium) Tablets](https://www.drugpatentwatch.com/drugs/lipitor)." DrugPatentWatch.com.
2. "Atorvastatin: drug information." [Mayo Clinic](https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20063022?p=1), 11 Jan. 2022.
3. "Muscle pain and statins." [Mayo Clinic](https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/muscle-pain/art-20045843), 11 Jan. 2022.
4. "Monounsaturated fat-rich diet reduces muscle and liver lipid content and lipotoxicity in statin-treated patients with hypercholesterolemia: a randomized controlled trial." [Journal of Clinical Lipidology](https://www.sciencedirect.com/science/article/pii/S1933287415003321), vol. 9, no. 3, 2015, pp. 455-466.
5. "Effects of dietary fat on atorvastatin pharmacokinetics and pharmacodynamics." [Clinical Pharmacology & Therapeutics](https://onlinelibrary.wiley.com/doi/abs/10.1038/clpt.2008.238), vol. 84, no. 6, 2008, pp. 733-739.