Lipitor, also known as atorvastatin, is a commonly prescribed medication for high cholesterol. However, muscle pain is a known side effect of this medication. The question of whether Lipitor muscle pain improves over time is a common concern among patients.

According to a study published on Drug Patent Watch [1], muscle pain was reported as a side effect in 2.5% of patients taking Lipitor. This muscle pain can range from mild to severe and can occur within weeks or months of starting the medication. However, the study did not provide information on whether this side effect improved over time.

A Harvard Health Publishing article [2] suggests that muscle pain caused by statins like Lipitor may improve over time. The article states that muscle pain often occurs within the first few weeks of starting the medication and may improve as the body adjusts to the drug. The article also recommends talking to a doctor about adjusting the dosage or switching to a different statin if the muscle pain persists.

However, in rare cases, Lipitor can cause a serious condition called rhabdomyolysis, which can lead to muscle breakdown and kidney damage [3]. If a patient experiences severe muscle pain, weakness, or dark urine, they should seek medical attention immediately.

In conclusion, while muscle pain is a common side effect of Lipitor, it is possible that it may improve over time as the body adjusts to the medication. However, patients should monitor their symptoms and talk to their doctor if the pain persists or becomes severe. It is also important to be aware of the rare but serious side effect of rhabdomyolysis and seek medical attention if necessary.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.health.harvard.edu/pain/managing-statin-muscle-pain
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/expert-answers/rhabdomyolysis/faq-20057817