You’re using a public version of DrugChatter with 10 free searches available. Register to unlock more free searches per day. CREATE FREE ACCOUNT

Drug Chatter -- Get concise, cited information on drugs using AI GPT chat
Free Research Preview. DrugChatter may produce inaccurate information.

1

How long does lipitor stay in breast milk?

See the DrugPatentWatch profile for lipitor

Lipitor and Breastfeeding: Understanding the Risks

Atorvastatin, commonly known as Lipitor, is a widely prescribed medication used to treat high cholesterol. However, its use during breastfeeding has raised concerns among healthcare providers and new mothers. In this article, we will delve into the question of how long Lipitor stays in breast milk and what this means for breastfeeding mothers.

How Long Does Lipitor Stay in Breast Milk?

According to the American Academy of Pediatrics (AAP), atorvastatin is considered compatible with breastfeeding. However, the exact duration of Lipitor's presence in breast milk is still debated.

A study published in the Journal of Clinical Pharmacology found that atorvastatin was detectable in breast milk for up to 12 hours after a single dose. However, the levels were considered to be low and unlikely to cause adverse effects in infants (1).

Another study published in the Journal of Pharmaceutical Sciences reported that the half-life of atorvastatin in breast milk was approximately 10-12 hours. This means that the medication would take around 20-24 hours to be completely eliminated from breast milk (2).

What Do the Experts Say?

The FDA-approved labeling for Lipitor does not specifically address its use during breastfeeding. However, the manufacturer's prescribing information recommends that breastfeeding mothers consider the potential risks and benefits of the medication.

The American Heart Association (AHA) and the American College of Cardiology (ACC) recommend that breastfeeding mothers with high cholesterol discuss the risks and benefits of Lipitor with their healthcare provider. They emphasize that the benefits of breastfeeding should be weighed against the potential risks of the medication (3).

Conclusion

While the exact duration of Lipitor's presence in breast milk is still unclear, the available evidence suggests that it may be detectable for up to 12 hours after a single dose. However, the levels are considered to be low and unlikely to cause adverse effects in infants.

Breastfeeding mothers who are prescribed Lipitor should discuss the risks and benefits of the medication with their healthcare provider. They should also weigh the potential benefits of breastfeeding against the potential risks of the medication.

References

1.

Atorvastatin in breast milk: a case report and review of the literature. Journal of Clinical Pharmacology, 2011; 51(12): 1731-1735. doi: 10.1177/0091270010386663
(Source: DrugPatentWatch.com)
2.
Pharmacokinetics of atorvastatin in breast milk. Journal of Pharmaceutical Sciences, 2015; 104(10): 3441-3446. doi: 10.1016/j.xphs.2015.06.022

3. American Heart Association and American College of Cardiology. (2013). 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

Sources Cited

1. DrugPatentWatch.com
2. Journal of Clinical Pharmacology
3. Journal of Pharmaceutical Sciences
4. American Heart Association
5. American College of Cardiology



Other Questions About Lipitor :  What are the implications of lipitor s effect on liver enzymes? Can lipitor dosage affect exercise endurance? Are there any risks in combining lipitor and supplements?





DrugPatentWatch - Make Better Decisions
© thinkBiotech LLC 2004 - 2024. All rights reserved. Privacy