Lipitor is a medication used to lower cholesterol levels in the body. Grapefruit and grapefruit juice can interact with Lipitor, which can increase the levels of the drug in the bloodstream, leading to potential side effects. Therefore, it is important to adjust the dosage of Lipitor when consuming grapefruit or grapefruit juice.

According to the FDA-approved label for Lipitor, patients should avoid consuming large quantities of grapefruit juice (more than 1 quart per day) while taking Lipitor. The label also recommends that patients who regularly consume grapefruit juice should consult with their healthcare provider to determine if a dosage adjustment is necessary [2].

The National Center for Biotechnology Information (NCBI) also recommends that patients taking Lipitor should avoid grapefruit and grapefruit juice, as they can increase the levels of the drug in the bloodstream [3]. The NCBI advises patients to speak with their healthcare provider about any potential interactions with grapefruit or grapefruit juice.

While the Drug Patent Watch website does not provide specific dosage adjustments for Lipitor and grapefruit, it does list grapefruit juice as a potential food interaction that should be avoided while taking Lipitor [1].

In summary, patients taking Lipitor should avoid consuming large quantities of grapefruit or grapefruit juice, and should consult with their healthcare provider to determine if a dosage adjustment is necessary. It is important to be aware of potential interactions between medications and food or beverages, and to speak with a healthcare provider if there are any concerns.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf
[3] https://www.ncbi.nlm.nih.gov/books/NBK532919/