Tylenol and Advil are two common over-the-counter pain relievers, but they work differently in the body. Tylenol, also known as acetaminophen, is a pain reliever and fever reducer that works by blocking pain signals to the brain. Advil, also known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing inflammation and blocking pain signals to the brain.

According to MercyCare [2], both Tylenol and Advil can be used to treat pain, fever, and inflammation, but they have different uses and potential side effects. Tylenol is generally considered safer for children and pregnant women, while Advil is better for reducing inflammation and swelling. Advil may also be more effective for certain types of pain, such as menstrual cramps or toothaches. However, Advil can cause stomach upset and may increase the risk of bleeding, especially if taken with blood-thinning medications. Tylenol can cause liver damage if taken in large doses or combined with alcohol.

UnityPoint [3] suggests that the choice between Tylenol and Advil depends on the type of pain you are experiencing and your individual health history. If you have a headache, muscle pain, or a fever, Tylenol may be a good choice. If you have menstrual cramps, back pain, or arthritis, Advil may be more effective. However, it is important to talk to your doctor or pharmacist before taking any medication, especially if you have a history of liver or kidney disease, stomach ulcers, or other medical conditions.

In conclusion, Tylenol and Advil are both effective pain relievers, but they work differently and have different potential side effects. The choice between the two depends on the type of pain you are experiencing and your individual health history. It is important to talk to your doctor or pharmacist before taking any medication.

Sources:
[2] https://www.mercycare.org/healthy-living/health-education/tylenol--advil--when-to-use-which/
[3] https://www.unitypoint.org/news-and-articles/acetaminophen-vs-ibuprofen-what-to-take-when.