After reviewing the available information, there is no definitive evidence to suggest that long-term Lipitor users are more prone to liver problems. Lipitor, also known as atorvastatin, is a statin medication used to lower cholesterol levels and reduce the risk of heart disease [1].

Statins have been associated with a minor increase in liver enzymes, which can be a sign of liver damage. However, this increase is usually mild and reversible, and most patients can continue taking the medication [2]. In rare cases, statins may cause severe liver problems, but this risk is not specific to Lipitor and applies to all statin medications [3].

It is important to note that Lipitor's label includes a warning about the potential for liver damage, but this warning is standard for all statin medications [4]. The label also states that liver enzyme tests should be performed before starting Lipitor and periodically thereafter [4].

In summary, while Lipitor and other statins have been linked to a small increase in liver enzymes, there is no evidence to suggest that long-term Lipitor users are more prone to liver problems. Patients taking Lipitor should be monitored for liver function, but the risk of liver damage is low and typically reversible.

Sources:
[1] Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063095>
[2] National Library of Medicine. (2021). Atorvastatin. Retrieved from <https://medlineplus.gov/druginfo/meds/a601263.html>
[3] American College of Gastroenterology. (2019). Statins and Liver Disease. Retrieved from <https://gi.org/topics/statins-and-liver-disease/>
[4] DrugPatentWatch. (2021). Lipitor (Atorvastatin Calcium). Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>