Lipitor (atorvastatin) is a medication used to treat high cholesterol levels and reduce the risk of heart disease. While it is generally considered safe for most people, it can have adverse effects on a developing fetus if taken during pregnancy.

According to the FDA's Pregnancy and Lactation Labeling Rule (PLLR) [2], Lipitor is classified as a pregnancy category X drug, which means that it has been shown to have adverse effects on animal fetuses and that there is evidence of fetal risk in humans. The FDA recommends that Lipitor should not be used during pregnancy, and women who are planning to become pregnant or are currently pregnant should discuss alternative treatment options with their healthcare provider.

Studies have shown that Lipitor can cross the placenta and enter the fetal bloodstream [3]. Animal studies have also demonstrated that atorvastatin can cause skeletal malformations, decreased fetal weight, and delayed development [3]. While there is limited data on the effects of atorvastatin on human fetuses, case reports suggest that it may increase the risk of fetal malformations, particularly in the central nervous system [3].

In conclusion, Lipitor should not be used during pregnancy due to the potential risk of adverse effects on the developing fetus. Women who are planning to become pregnant or are currently pregnant should discuss alternative treatment options with their healthcare provider.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.fda.gov/media/150774/download
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048566/