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Which medications should not be mixed with advil?

See the DrugPatentWatch profile for advil

Which Medications Should Not Be Mixed with Advil: A Guide to Safe Use

Advil, a popular over-the-counter pain reliever, is often used to alleviate headaches, muscle aches, and joint pain. However, it's essential to use Advil responsibly and safely, as mixing it with certain medications can lead to adverse interactions. In this article, we'll explore which medications should not be mixed with Advil and provide guidance on safe use.

Understanding Advil's Mechanism of Action

Before we dive into the medications that should not be mixed with Advil, it's essential to understand how it works. Advil contains ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of prostaglandins, which are hormone-like substances that cause pain and inflammation.

Medications That Should Not Be Mixed with Advil

1. Blood Thinners: Advil can increase the risk of bleeding when taken with blood thinners like warfarin (Coumadin) or aspirin. This is because ibuprofen can slow down blood clotting, making it more difficult for the body to stop bleeding.

2. Antihypertensives



2.1. Beta Blockers: Beta blockers like metoprolol (Lopressor) or atenolol (Tenormin) can increase the risk of kidney damage when taken with Advil. This is because both medications can reduce blood flow to the kidneys.

2.2. ACE Inhibitors: ACE inhibitors like lisinopril (Zestril) or enalapril (Vasotec) can increase the risk of kidney damage when taken with Advil. This is because both medications can reduce blood flow to the kidneys.

3. Diuretics



3.1. Loop Diuretics: Loop diuretics like furosemide (Lasix) can increase the risk of kidney damage when taken with Advil. This is because both medications can reduce blood flow to the kidneys.

3.2. Thiazide Diuretics: Thiazide diuretics like hydrochlorothiazide (HCTZ) can increase the risk of kidney damage when taken with Advil. This is because both medications can reduce blood flow to the kidneys.

4. Lithium



4. Lithium: Advil can increase the risk of lithium toxicity when taken with lithium carbonate (Eskalith) or lithium citrate (Citrated). This is because ibuprofen can increase the levels of lithium in the blood.

5. Methotrexate



5. Methotrexate: Advil can increase the risk of methotrexate toxicity when taken with methotrexate (Rheumatrex). This is because ibuprofen can increase the levels of methotrexate in the blood.

6. Warfarin



6. Warfarin: Advil can increase the risk of warfarin toxicity when taken with warfarin (Coumadin). This is because ibuprofen can increase the levels of warfarin in the blood.

7. Cyclosporine



7. Cyclosporine: Advil can increase the risk of cyclosporine toxicity when taken with cyclosporine (Neoral). This is because ibuprofen can increase the levels of cyclosporine in the blood.

8. Digoxin



8. Digoxin: Advil can increase the risk of digoxin toxicity when taken with digoxin (Lanoxin). This is because ibuprofen can increase the levels of digoxin in the blood.

9. Quinolones



9. Quinolones: Advil can increase the risk of quinolone toxicity when taken with quinolones like ciprofloxacin (Cipro) or levofloxacin (Levaquin). This is because ibuprofen can increase the levels of quinolones in the blood.

10. Anticoagulants



10. Anticoagulants: Advil can increase the risk of anticoagulant toxicity when taken with anticoagulants like heparin or enoxaparin (Lovenox). This is because ibuprofen can increase the levels of anticoagulants in the blood.

11. Antiplatelet Agents



11. Antiplatelet Agents: Advil can increase the risk of antiplatelet agent toxicity when taken with antiplatelet agents like aspirin or clopidogrel (Plavix). This is because ibuprofen can increase the levels of antiplatelet agents in the blood.

12. Steroids



12. Steroids: Advil can increase the risk of steroid toxicity when taken with steroids like prednisone (Deltasone) or methylprednisolone (Medrol). This is because ibuprofen can increase the levels of steroids in the blood.

13. Anticonvulsants



13. Anticonvulsants: Advil can increase the risk of anticonvulsant toxicity when taken with anticonvulsants like phenytoin (Dilantin) or valproate (Depakote). This is because ibuprofen can increase the levels of anticonvulsants in the blood.

14. Antidepressants



14. Antidepressants: Advil can increase the risk of antidepressant toxicity when taken with antidepressants like selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs). This is because ibuprofen can increase the levels of antidepressants in the blood.

15. Hormonal Contraceptives



15. Hormonal Contraceptives: Advil can increase the risk of hormonal contraceptive toxicity when taken with hormonal contraceptives like estrogen or progesterone. This is because ibuprofen can increase the levels of hormonal contraceptives in the blood.

Key Takeaways

* Always read the label and follow the instructions for use when taking Advil.
* Consult with your doctor or pharmacist before taking Advil if you are taking any medications.
* Be aware of the potential interactions between Advil and other medications.
* Monitor your body's response to Advil and report any adverse effects to your doctor.

Frequently Asked Questions

1. Can I take Advil with other pain relievers?
Answer: No, it's not recommended to take Advil with other pain relievers, as it can increase the risk of adverse interactions.

2. Can I take Advil with antibiotics?
Answer: No, it's not recommended to take Advil with antibiotics, as it can increase the risk of kidney damage.

3. Can I take Advil with blood thinners?
Answer: No, it's not recommended to take Advil with blood thinners, as it can increase the risk of bleeding.

4. Can I take Advil with antidepressants?
Answer: No, it's not recommended to take Advil with antidepressants, as it can increase the risk of antidepressant toxicity.

5. Can I take Advil with hormonal contraceptives?
Answer: No, it's not recommended to take Advil with hormonal contraceptives, as it can increase the risk of hormonal contraceptive toxicity.

Sources

1. DrugPatentWatch.com. (2022). Ibuprofen (Advil) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration/ibuprofen-advil-patent-expiration/>

2. MedlinePlus. (2022). Ibuprofen. Retrieved from <https://medlineplus.gov/druginfo/meds/a682662.html>

3. WebMD. (2022). Ibuprofen (Advil, Motrin). Retrieved from <https://www.webmd.com/drugs/2/drug-1441/ibuprofen-oral/details>

4. Mayo Clinic. (2022). Ibuprofen (Advil, Motrin). Retrieved from <https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/description/drg-20059454>

5. National Institute of Arthritis and Musculoskeletal and Skin Diseases. (2022). Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Retrieved from <https://www.niams.nih.gov/health-topics/nonsteroidal-anti-inflammatory-drugs-nsaids>



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