The use of Lipitor (atorvastatin), a cholesterol-lowering drug, and Selective Serotonin Reuptake Inhibitors (SSRIs), a type of antidepressant, concurrently does not directly lead to muscle harm. However, both Lipitor and SSRIs can independently increase the risk of muscle-related side effects [1].

Lipitor, like other statins, carries a risk of muscle-related side effects, such as myalgia (muscle pain) and, more rarely, rhabdomyolysis (severe muscle breakdown) [1][2]. The risk of muscle-related side effects with Lipitor is generally low, and the benefits of Lipitor in reducing the risk of heart attack and stroke usually outweigh the potential risks [1].

SSRIs, on the other hand, have not been directly associated with muscle harm [1]. However, some SSRIs, such as fluoxetine and paroxetine, can increase the blood levels of statins like Lipitor, which may enhance the risk of muscle-related side effects [1][2].

It is essential to monitor patients taking both Lipitor and SSRIs for muscle-related side effects, and healthcare providers should consider dose adjustments or alternative treatments if necessary [1]. Patients should consult their healthcare providers before starting or stopping any medication.

In summary, concurrent Lipitor and SSRI use does not directly lead to muscle harm, but both medications can increase the risk of muscle-related side effects. Healthcare providers should monitor patients taking both medications closely and consider dose adjustments or alternative treatments if necessary.

Sources:
[1] <https://www.ncbi.nlm.nih.gov/books/NBK64821/>
[2] <https://www.drugs.com/drug-interactions/atorvastatin-with-fluoxetine-3833-195-195-195-195.html>
[3] <https://www.drugpatentwatch.com/drugs/lipitor>