After analyzing the sources provided, there is no direct evidence that avocado affects the effectiveness of Lipitor. Lipitor is a medication used to lower cholesterol levels in the body, specifically low-density lipoprotein (LDL) cholesterol, which is considered the "bad" cholesterol. It works by blocking the enzyme that produces cholesterol in the liver [1].

Avocado is a fruit that is rich in healthy fats, fiber, vitamins, and minerals. It has been associated with reducing cholesterol levels in the body, particularly LDL cholesterol. A study published in the Journal of Clinical Lipidology found that a diet rich in avocados decreased LDL cholesterol levels in overweight and obese individuals [2].

However, there is no evidence to suggest that consuming avocado affects the effectiveness of Lipitor. It is important to note that consuming large amounts of avocado may increase calorie and fat intake, which can lead to weight gain and potentially negatively impact cholesterol levels. It is recommended to consume avocado in moderation as part of a balanced diet [3].

In conclusion, while avocado has been associated with reducing cholesterol levels, there is no direct evidence to suggest that it affects the effectiveness of Lipitor. It is important to consult with a healthcare professional before making any changes to medication or dietary habits.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330060/
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/cholesterol/art-20045192