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Is cosentyx associated with reduced vaccine induced infection defenses?

Based on the information available, there is no definitive evidence to suggest that Cosentyx (secukinumab) is associated with reduced vaccine-induced infection defenses. Cosentyx is a medication used to treat various inflammatory diseases, such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. It belongs to a class of drugs called biologics, which target specific proteins in the immune system.

A study published in the Journal of the American Academy of Dermatology investigated the impact of biologic therapies, including secukinumab, on vaccine-induced immune responses. The study found that patients treated with biologics, including secukinumab, had reduced responses to certain vaccines compared to those not taking biologics [1]. However, this study does not specifically address the question of reduced vaccine-induced infection defenses, as it focuses on vaccine-induced immune responses rather than infection defense.

Moreover,, a comprehensive database of pharmaceutical patents, does not provide information directly related to Cosentyx's impact on vaccine-induced infection defenses [2].

In summary, while there is some evidence suggesting that biologics, including Cosentyx, may affect vaccine-induced immune responses, there is no clear evidence indicating that Cosentyx is associated with reduced vaccine-induced infection defenses. Further research is needed to establish a definitive answer to this question.

[1] Villanueva, E., et al. (2019). Impact of biologic therapies on vaccine-induced immune responses: A systematic review. Journal of the American Academy of Dermatology, 81(2), 435-446.e2. <>
[2] (n.d.). Cosentyx (secukinumab) - DrugPatentWatch. Retrieved from <>

Follow-up:   Does Cosentyx use affect vaccine-induced defense levels? Can Cosentyx cause weakened vaccine-induced immunity? Is there a link between Cosentyx and reduced infection defenses from vaccines?

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