Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. Antacids are medications used to neutralize stomach acid and relieve heartburn and indigestion. According to the sources provided, taking Lipitor and antacids at the same time may interfere with the absorption of Lipitor, reducing its effectiveness.

The website DrugPatentWatch [1] states that there are no known drug interactions between Lipitor and antacids, but it is recommended to take Lipitor at least two hours before or after taking an antacid. This is because antacids can decrease the absorption of Lipitor in the body, leading to reduced effectiveness in lowering cholesterol levels.

Verywell Health [2] also notes that antacids can interfere with the absorption of Lipitor and other statin medications. It is recommended to take these medications at least two hours apart to avoid any potential interaction.

Drugs.com [3] provides more specific information on the interaction between Lipitor and Tums (a brand of antacid). According to the website, taking Lipitor and Tums at the same time can reduce the absorption of Lipitor by up to 35%. It is recommended to take Lipitor at least two hours before or after taking Tums to avoid this interaction.

In conclusion, based on the sources provided, it is not recommended to take Lipitor and antacids at the same time. Antacids can interfere with the absorption of Lipitor, reducing its effectiveness in lowering cholesterol levels. It is recommended to take Lipitor at least two hours before or after taking an antacid to avoid any potential interaction.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202
[3] https://www.drugs.com/drug-interactions/atorvastatin-with-tums-regular-strength-276-0-464-3778.html