Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels and prevent heart disease [1]. Vitamin D, on the other hand, is a nutrient that helps the body absorb calcium and maintain bone health [3].

According to the Drug Patent Watch website, Lipitor has a number of potential side effects, including muscle pain, weakness, and tenderness, as well as liver problems and allergic reactions [1]. However, there is no mention of any adverse reactions between Lipitor and vitamin D on this website.

A study published in the National Center for Biotechnology Information found that taking atorvastatin (Lipitor) in combination with vitamin D may have a positive effect on cardiovascular disease risk factors, such as inflammation and oxidative stress [2]. The study also noted that there were no significant adverse effects observed in the participants who took both atorvastatin and vitamin D.

The Mayo Clinic states that taking high doses of vitamin D supplements can cause adverse reactions, such as nausea, vomiting, and constipation, as well as kidney damage and high blood calcium levels [3]. However, if taken in recommended doses, vitamin D is generally considered safe.

In conclusion, while Lipitor has potential side effects, there is no evidence of adverse reactions between Lipitor and vitamin D. In fact, taking both medications may have a positive effect on cardiovascular disease risk factors. However, it is important to follow recommended doses of vitamin D to avoid potential adverse reactions. As with any medication or supplement, it is always best to consult with a healthcare professional before starting a new regimen.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644425/
[3] https://www.mayoclinic.org/drugs-supplements-vitamin-d/art-20363792