Lipitor is a medication used to lower cholesterol levels in the blood [1]. According to the Mayo Clinic, Lipitor is a type of statin drug that can cause side effects such as muscle pain, liver damage, and digestive problems [2]. The Harvard Health Blog states that grapefruit juice can interact with certain statin drugs, including Lipitor, which can increase the risk of side effects [3]. However, there is no evidence to suggest that grapefruit oil has any effect on the effectiveness of Lipitor.

In conclusion, while grapefruit juice can interact with Lipitor and increase the risk of side effects, there is no evidence to suggest that grapefruit oil has any effect on the effectiveness of the medication. Patients taking Lipitor should talk to their doctor about any potential interactions with other medications or supplements.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013
[3] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins