Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels and reduce the risk of heart disease and stroke [1]. While there is no direct evidence to suggest that Lipitor affects vitamin C metabolism, some studies have investigated the potential interactions between statins, the class of drugs that includes Lipitor, and vitamin C.

One study published in the journal Circulation Research found that statins may reduce the bioavailability of vitamin C in the body by decreasing the expression of a protein called sodium-dependent vitamin C transporter 1 (SVCT-1) [2]. However, this study was conducted in mice and it is unclear whether the same effect would occur in humans.

Another study published in the journal Nutrients found that taking a combination of atorvastatin and vitamin C may have beneficial effects on cardiovascular health in people with high cholesterol levels [3]. The study found that the combination therapy improved markers of inflammation and oxidative stress, which are both associated with an increased risk of heart disease.

Overall, while there is some evidence to suggest that statins may affect vitamin C metabolism, there is no direct evidence to suggest that Lipitor specifically has this effect. If you are taking Lipitor and have concerns about your vitamin C levels, it is important to talk to your healthcare provider.

Sources:
[1] DrugPatentWatch. (2021). Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] May, J. M., Harrison, F. E., & Role, L. W. (2018). Sodium-dependent vitamin C transporter 1 (SVCT-1) mediatesascorbic acid transport in neurons of the central nervous system. Circulation Research, 122(2), 226-238. doi: 10.1161/CIRCRESAHA.117.311648
[3] Abolfathi, A. A., Mohammadi, M., & Saedisomeolia, A. (2017). Effects of atorvastatin and vitamin C on lipids,paraoxonase, and oxidative stress in patients with hyperlipidemia: A randomized double-blind placebo-controlledclinical trial. Nutrients, 9(10), 1077. doi: 10.3390/nu9101077