Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. Combining these two drugs may increase the risk of side effects.

According to GoodRx [3], taking Lipitor and ibuprofen together may increase the risk of gastrointestinal bleeding and kidney damage. This is because ibuprofen can interfere with the blood-thinning effects of Lipitor, which can lead to bleeding in the stomach or intestines. In addition, both drugs can affect the kidneys, and combining them may increase the risk of kidney damage.

The Mayo Clinic [2] warns that taking ibuprofen regularly can also increase the risk of heart attack or stroke, which may be of particular concern for people taking Lipitor to reduce their risk of cardiovascular disease. This risk may be higher in people with pre-existing heart disease or other risk factors for cardiovascular disease.

Drug Patent Watch [1] notes that while there are no specific drug interactions listed between Lipitor and ibuprofen, patients should always consult with their doctor or pharmacist before taking any new medications, including over-the-counter drugs like ibuprofen. They also advise that patients should inform their healthcare provider if they experience any unusual side effects while taking these medications together.

In conclusion, taking Lipitor and ibuprofen together may increase the risk of gastrointestinal bleeding, kidney damage, and cardiovascular events. Patients should always consult with their healthcare provider before taking any new medications and should inform them of any unusual side effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/drugs-supplements-ginkgo/art-20362032
[3] https://www.goodrx.com/atorvastatin/interactions