Aspirin and Lipitor are two commonly prescribed medications that are used to treat different conditions. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, reduce inflammation, and prevent blood clots. Lipitor, on the other hand, is a statin drug that is used to lower cholesterol levels in the blood.

According to a study published in Frontiers in Pharmacology [3], there is no evidence to suggest that aspirin affects the dosage of Lipitor. The study states that both aspirin and Lipitor are metabolized by different enzymes in the liver, and there is no known interaction between the two drugs that would affect their metabolism or efficacy.

However, it is important to note that taking aspirin and Lipitor together may increase the risk of bleeding, especially in individuals who are at high risk of bleeding. This is because aspirin can thin the blood and increase the risk of bleeding, while Lipitor can also increase the risk of bleeding in some individuals. Therefore, it is important to consult with a healthcare provider before taking these medications together [2].

In conclusion, there is no evidence to suggest that aspirin affects the dosage of Lipitor. However, taking these medications together may increase the risk of bleeding, and it is important to consult with a healthcare provider before taking them together [3].

Sources:
[2] https://www.healthcentral.com/article/aspirin-lipitor-time
[3] https://www.frontiersin.org/articles/10.3389/fphar.2021.589418/full