Yes, grapefruit juice can affect Lipitor medication. Lipitor, also known as atorvastatin, is a type of drug called a statin, which is used to lower cholesterol levels in the blood [1]. According to the Harvard Health Publishing, consuming grapefruit juice while taking Lipitor can increase the amount of medication in the body, which can increase the risk of side effects [2].

The active compounds in grapefruit juice, called furanocoumarins, can interfere with the body's ability to break down Lipitor, leading to higher levels of the drug in the bloodstream [3]. This can increase the risk of side effects such as muscle pain, liver damage, and kidney damage [2].

It is important to note that not all statins are affected by grapefruit juice in the same way. Lipitor is one of the statins that can interact with grapefruit juice [3]. Other statins, such as rosuvastatin (Crestor) and pravastatin (Pravachol), are not affected by grapefruit juice [2].

It is recommended that individuals taking Lipitor should avoid consuming grapefruit juice [2]. If you have any concerns about your medication and diet, it is best to consult with your healthcare provider [3].

Sources:

* <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
* <https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins>
* <https://www.verywellhealth.com/can-i-take-lipitor-or-zocor-with-grapefruit-juice-1124045>