Yes, there are indeed herbal supplements that can interact with Lipitor, a medication commonly used to treat high cholesterol.

Lipitor, also known as atorvastatin, can interact with various herbal supplements, potentially leading to adverse effects or reduced drug effectiveness. According to Drugs.com, some of these herbal supplements include [1]:

1. Red yeast rice: This supplement contains monacolin K, which is a statin similar to atorvastatin. Combining the two can increase the risk of muscle damage and liver problems.

2. Garlic: While garlic can help lower cholesterol levels, it can also increase the risk of bleeding when taken with Lipitor, especially if you're also using blood-thinning medications.

3. St. John's Wort: This herb can decrease the effectiveness of Lipitor by speeding up its metabolism in the liver.

4. Ginkgo Biloba: This herb may increase the risk of bleeding when taken with Lipitor, especially if you're also using blood-thinning medications.

5. Ginseng: This herb can interact with Lipitor by affecting blood sugar levels and the immune system.

It is crucial to consult with a healthcare provider before starting any herbal supplement while on Lipitor or any other medication. This information is based on sources [1] and [2].

Sources:
[1] Drugs.com. (n.d.). Atorvastatin Interactions. Retrieved from https://www.drugs.com/drug-interactions/atorvastatin,herbal-supplements.html
[2] DrugPatentWatch. (2021). Lipitor (Atorvastatin) Drug Patent Expiration & Generic Launch Dates. Retrieved from https://www.drugpatentwatch.com/drugs/lipitor/expiration-dates