Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the sources provided, there is some evidence to suggest that taking Lipitor at night may increase its effectiveness.

One reason for this is that the body produces more cholesterol at night, so taking Lipitor at this time may help to target this excess cholesterol [2]. Additionally, research has shown that taking Lipitor at night can lead to a greater reduction in LDL (bad) cholesterol levels compared to taking it in the morning [3].

However, it is important to note that the optimal time to take Lipitor may vary depending on the individual and their specific health needs. It is recommended to follow the instructions provided by your healthcare provider or pharmacist regarding the timing of Lipitor administration [2].

It is also important to be aware of the potential side effects of Lipitor, which can include muscle pain, weakness, and liver problems [2]. If you experience any concerning symptoms while taking Lipitor, it is important to contact your healthcare provider right away.

In summary, while there is some evidence to suggest that taking Lipitor at night may increase its effectiveness, the optimal time to take the medication may vary depending on the individual. It is recommended to follow the instructions provided by your healthcare provider or pharmacist regarding the timing of Lipitor administration, and to be aware of the potential side effects of the medication.

Sources:
[2] Mayo Clinic. Atorvastatin (Oral Route): Side Effects. Retrieved from https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20067003
[3] Healthline. Why Should You Take Statins at Night? Retrieved from https://www.healthline.com/health/high-cholesterol/why-should-you-take-statins-at-night
[4] Drug Patent Watch. Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR