Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood, while garlic has been shown to have some cholesterol-lowering effects. However, there is limited information on the interaction between garlic and Lipitor.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and garlic. However, it is important to note that this information does not necessarily mean that there are no interactions between these two substances.

A study published in the Journal of Clinical Pharmacology [2] found that garlic did not have a significant effect on the pharmacokinetics of atorvastatin. The study was conducted on healthy volunteers who were given atorvastatin alone or with garlic supplements. The results showed that the garlic supplements did not affect the absorption, distribution, metabolism, or elimination of atorvastatin.

Another study published in the Journal of Agricultural and Food Chemistry [3] found that garlic extract could enhance the cholesterol-lowering effects of atorvastatin in rats. The study suggests that garlic extract may have a synergistic effect with atorvastatin in reducing cholesterol levels. However, it is important to note that this study was conducted on rats, and further research is needed to determine if the same effect occurs in humans.

In conclusion, there is limited information on the interaction between garlic and Lipitor. While there are no known drug interactions between these two substances, it is important to consult with a healthcare professional before taking garlic supplements while on Lipitor. Additionally, while one study suggests that garlic extract may enhance the cholesterol-lowering effects of atorvastatin, further research is needed to determine the safety and effectiveness of this combination in humans.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997463/
[3] https://pubmed.ncbi.nlm.nih.gov/21170253/