Lipitor is a brand name for atorvastatin, a medication used to lower cholesterol levels in the blood [1]. According to the sources provided, there is no specific mention of orange juice interacting negatively with Lipitor. However, it is important to note that grapefruit juice has been shown to interact with statins, a class of drugs that includes Lipitor [2]. Grapefruit juice can increase the absorption of statins, leading to higher levels of the drug in the bloodstream, which can increase the risk of side effects [3]. It is not clear if orange juice has a similar effect on statins, but it is generally recommended to avoid consuming large amounts of citrus fruits while taking statins, including Lipitor, to reduce the risk of potential interactions [2]. It is important to consult with a healthcare provider or pharmacist before making any changes to medication or diet to ensure safe and effective treatment.

Sources:
[1] DrugPatentWatch. (n.d.). Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] WellRx. (n.d.). Lipitor: Lifestyle Interactions. Retrieved from https://www.wellrx.com/lipitor/lifestyle-interactions/
[3] Healthline. (2019, May 15). Grapefruit and Statins: Why Mix? Retrieved from https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins