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Are there any unique risks for younger patients taking methotrexate?



Methotrexate is a medication used to treat various medical conditions, including cancer, autoimmune diseases, and psoriasis. According to the sources provided, there are some unique risks for younger patients taking methotrexate.

One of the potential risks associated with methotrexate use in younger patients is the development of liver damage [1]. Methotrexate is known to be toxic to the liver, and younger patients may be more susceptible to liver damage due to their immature liver function [2]. Therefore, close monitoring of liver function is essential in younger patients taking methotrexate.

Another risk associated with methotrexate use in younger patients is the potential for growth problems [3]. Methotrexate can affect the body's ability to produce new cells, which can lead to growth problems in children. Therefore, it is important to monitor growth in younger patients taking methotrexate.

Additionally, methotrexate can cause adverse effects on the immune system, which can lead to an increased risk of infections [2]. Younger patients may be more susceptible to infections due to their immature immune systems. Therefore, it is important to monitor for signs of infection in younger patients taking methotrexate.

In conclusion, younger patients taking methotrexate may be at risk for liver damage, growth problems, and an increased risk of infections. Close monitoring of liver function, growth, and signs of infection is essential in younger patients taking methotrexate.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/METHOTREXATE
[2] https://ascopubs.org/doi/10.1200/jco.2015.62.4544
[3] https://www.ncbi.nlm.nih.gov/books/NBK556114/



Follow-up:   What are the dosage recommendations for methotrexate in younger patients? Are there any long-term effects of methotrexate use in younger patients? How does methotrexate interact with other medications in younger patients?





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