Lipitor is a brand name for the drug atorvastatin, which belongs to the class of medications called statins. Statins are commonly used to lower cholesterol levels in the blood. According to GoodRx [2], grapefruit can interact with certain statins, including Lipitor, and increase the risk of side effects. Grapefruit contains compounds that can interfere with the metabolism of certain drugs, including statins. This can lead to increased levels of the drug in the blood, which can increase the risk of side effects.

Healthline [3] explains that the interaction between grapefruit and Lipitor can cause an increase in the concentration of Lipitor in the blood, which can lead to an increased risk of side effects such as muscle pain, liver damage, and kidney failure. The severity of the side effects can vary depending on the individual and the dose of the drug. Therefore, it is important to avoid consuming grapefruit or grapefruit juice while taking Lipitor.

In summary, grapefruit can interact with Lipitor and increase the risk of side effects. Patients taking Lipitor should avoid consuming grapefruit or grapefruit juice. It is always important to consult with a healthcare provider or pharmacist before taking any new medication or changing your diet.

Sources:
[2] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin
[3] https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins