Lipitor is a brand name for atorvastatin, a medication used to lower cholesterol levels in the blood [1]. Antidepressants are a class of medications used to treat depression and other mental health disorders. According to a study published in the journal Psychopharmacology, there is a potential risk of drug interactions between atorvastatin and certain antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) [2]. These interactions can lead to an increased risk of side effects, including serotonin syndrome, a potentially life-threatening condition that can cause high fever, seizures, and irregular heartbeat [2]. However, the study notes that not all patients who take both atorvastatin and antidepressants will experience these side effects, and the risk can vary depending on the specific medications and dosages involved [2]. It is important for patients who are taking both atorvastatin and antidepressants to discuss the potential risks and benefits with their healthcare provider, and to report any unusual symptoms or side effects that may occur. Additionally, patients should not stop taking either medication without consulting their healthcare provider first.

While the sources do not specifically mention Pfizer's COVID pills, it is important to note that any new medication or treatment should be discussed with a healthcare provider before combining it with other medications [3].

Sources:
[1] DrugPatentWatch. Lipitor. https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Wang, Y., et al. (2021). Drug-drug interaction between atorvastatin and antidepressants: a retrospective study. Psychopharmacology, 238, 2733-2741. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827898/
[3] NBC News. Pfizer's Covid pills for Covid symptoms may be risky with other drugs. https://www.nbcnews.com/health/health-news/pfizer-covid-pills-covid-symptoms-may-risky-drugs-rcna9683