Delgocitinib patent large scale synthesis?

Is there any public patent or synthesis data for delgocitinib at large scale?

I can’t confirm any public “large scale synthesis” route for delgocitinib from the information provided here, because no patents, publications, filings, or synthesis documents are included in your prompt. Without a specific document (e.g., WO/EP/US application number, assignee, or a link), I can’t reliably describe the manufacturing process, intermediates, or scale-up strategy.

Which patent should I look at for delgocitinib manufacturing / process chemistry?

If your goal is large-scale synthesis, the most relevant filings are usually process-focused patent families that include terms like “process for preparing,” “preparation,” “manufacture,” “intermediate,” or specific route steps tied to named intermediates. To pinpoint what you need, share any of the following and I’ll extract the large-scale-relevant steps and constraints from that text:

- Any patent publication number(s) (WO…, EP…, US…)
- The assignee/company name that owns the delgocitinib IP
- Links to the patent application(s)
- The specific intermediate or reaction step you want scaled (e.g., a key coupling, hydrogenation, cyclization, resolution step)

What details matter most for “large scale” synthesis patents?

In process patents, scale-up usually hinges on practical constraints. When you provide a patent text or link, I’ll focus on the sections that typically include:

- Solvent choices and solvent volumes (and whether they’re switched for scale)
- Temperature/pressure ranges and reaction duration
- Workup and purification strategy (e.g., extraction vs. chromatography; crystallization form)
- Yields and impurity controls for each step
- Use of catalysts/reagents and their recoverability
- Handling of hazardous steps (e.g., strong oxidants, azides, high-pressure hydrogenation)
- Salt formation and polymorph/crystal form control for the final API

Can you paste the patent claims/sections you have, and I’ll map them to a scale-up route?

If you paste the relevant patent excerpt (or upload the text) covering the synthesis and examples, I can:

- Identify which steps are likely candidates for scale-up
- Translate the example conditions into a manufacturing-style sequence
- Highlight risk points (exotherms, gas evolution, unstable intermediates, purification bottlenecks)
- Point out any “comparative” or “preferred” embodiments that indicate scale readiness

What I need from you to proceed

Send at least one of the following:

1) A delgocitinib patent publication number (WO/EP/US)
or
2) A link to the patent application
or
3) The synthesis example text you want analyzed

Once I have that, I can summarize the large-scale synthesis route described in the document and pull out the specific process parameters that control scale.