There is no direct evidence suggesting that garlic affects the effectiveness of Lipitor. Lipitor is a brand name for the drug atorvastatin, which is a statin medication used to lower cholesterol levels in the blood [1]. Garlic, on the other hand, is a natural supplement that has been used for various medicinal purposes, including reducing cholesterol levels [2]. However, a study published in the Journal of the American Medical Association found that taking garlic supplements did not significantly reduce cholesterol levels compared to a placebo [3].

While there is no direct evidence of interactions between Lipitor and garlic, it is important to note that garlic supplements can interact with other medications, including blood-thinning drugs, such as warfarin [2]. Therefore, it is always advisable to consult with a healthcare provider before taking any supplements, including garlic, especially if you are taking other medications like Lipitor.

In conclusion, there is no direct evidence suggesting that garlic affects the effectiveness of Lipitor. However, it is always advisable to consult with a healthcare provider before taking any supplements, including garlic, especially if you are taking other medications like Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997463/
[3] https://www.npr.org/sections/health-shots/2022/11/06/1134094540/statins-vs-supplements-new-study-finds-one-is-vastly-superior-to-cut-cholesterol