Lipitor is a medication used to lower cholesterol levels in the body, while probiotics are supplements that contain beneficial bacteria that help to improve gut health. There is limited research on the potential interaction between these two substances, but the available evidence suggests that probiotics are unlikely to reduce the effectiveness of Lipitor.

According to DrugPatentWatch [1], the active ingredient in Lipitor is atorvastatin, which works by inhibiting an enzyme that is involved in the production of cholesterol in the liver. Probiotics, on the other hand, do not contain any active ingredients that are known to interact with atorvastatin.

A study published in the Journal of Clinical Pharmacy and Therapeutics [2] found that probiotics did not have a significant effect on the pharmacokinetics of atorvastatin. The study involved 24 healthy volunteers who were given atorvastatin with or without a probiotic supplement for 14 days. The researchers found that there was no significant difference in the levels of atorvastatin in the blood between the two groups.

ConsumerLab [3] also states that there is no known interaction between probiotics and statins, including Lipitor. However, they caution that it is always important to consult with a healthcare professional before taking any new supplements or medications, as individual factors may affect how different substances interact in the body.

In conclusion, based on the available evidence, it appears that taking probiotics is unlikely to reduce the effectiveness of Lipitor. However, as with any supplement or medication, it is important to consult with a healthcare professional before taking them together to ensure that there are no potential interactions or adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904929/
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/